Through termination of cold war and in the way of attempts of U.S.A for continuing cooperation with newly established powerful counties in order to obtain modern global discipline the relationships between U.S.A and India was increased and reached to its climax during presidency of George Bush. Nevertheless, this growth of bilateral relationship was very reduced by selecting Obama as president of U.S.A. Therefore, this question is raised that what is the main reason for reducing bilateral relationship between U.S.A and India during presidency of Obama? It seems that incompatibility of U.S.A and India benefits and changing attitude of U.S.A toward global problems, regional and international rivals during presidency of Obama, is of the principal reasons of reducing their bilateral relationship. Whereas importance of cooperation between India and U.S.A and great influence for mutual relationship of both countries as important variable, this article investigates political-security relationship of U.S.A and India and related evolutions after presidency of Obama from 2008 until 2012.